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Abiogenèse - Un scénario plus nuancé


Posté par Noé , Aug 23,2002,11:36 Index  Forum

J'avais inclus une référence URL à ces travaux dans un message antérieur.

Une référence que Julien s'est empressé de ne pas considérer (diagonale oblige !)

Donc je n'écris pas pour ce cancre-là(t) !

Mais pour ceux que ça intéresse...

"...This started Prof. Doron Lancet of the Molecular Genetics Department in the Weizmann Institute of Science, and his students, Daniel Segre and
Dafna Ben-Eli, on a journey leading to alternatives to proteins and RNA.
They have developed a model, suggesting a new route for the origin of life, based on lipid molecules. This model is described in an article published a recent issue of the Proceedings of the National Academy of Science, USA..."

http://wis-wander.weizmann.ac.il/weizmann/doa_iis.dll/Serve/item/English/1.200.6.14.html

Un document (format PDF) à télécharger:
http://ool.weizmann.ac.il/Segre_Lipid_World.pdf

Également...


Compositional genomes: Prebiotic information transfer
in mutually catalytic noncovalent assemblies

Daniel Segré, Dafna Ben-Eli, and Doron Lancet

Résumé à:
http://www.pnas.org/cgi/content/abstract/97/8/4112

"...An alternative appears to be necessary for the RNA-centric paradigm of the origin of life. While RNA must have had a central role at some point in cellular evolution, it may have not been the first and only player (Lahav, 1991; Segré and Lancet, 1999). Rather, life on our planet could have begun as a random chemistry melting pot, a ‘garbage-bag world’ (Dyson, 1999), with myriads of different chemical configurations (Morowitz, 1992; Segré and Lancet, 1999; Yarus, 1999). In a more restricted analogy, it has been proposed that the presently known RNA chemistry emerged from a large ‘gemisch’ of nucleotide analogs (Sievers and von-Kiedrowski, 1994; de Duve, 1995; Bolli et al., 1997; Wills and Bada, 2000)..."

Texte complet à:
http://embo-reports.oupjournals.org/cgi/content/full/1/3/217


Voir également:
http://bioinformatics.weizmann.ac.il/cards/doron.html