: J Appl Physiol 1999 Oct;87(4):1381-5
Effect of supplementation with a cysteine donor on muscular performance.
Lands LC, Grey VL, Smountas AA
Division of Respiratory Medicine, McGill University Health
Centre-Montreal Children's Hospital, Montreal, Quebec, Canada H3H
1P3. larry.lands@muhc.mcgill.ca
Resumé
Oxidative stress contributes to muscular fatigue. GSH is the major
intracellular antioxidant, the biosynthesis of which is dependent on
cysteine availability. We hypothesized that supplementation with a
whey-based cysteine donor [Immunocal (HMS90)] designed to augment
intracellular GSH would enhance performance. Twenty healthy young
adults (10 men, 10 women) were studied presupplementation and 3 mo
postsupplementation with either Immunocal (20 g/day) or casein placebo.
Muscular performance was assessed by whole leg isokinetic cycle
testing, measuring peak power and 30-s work capacity. Lymphocyte
GSH was used as a marker of tissue GSH. There were no baseline
differences (age, ht, wt, %ideal wt, peak power, 30-s work capacity).
Follow-up data on 18 subjects (9 Immunocal, 9 placebo) were analyzed.
Both peak power [13 +/- 3.5 (SE) %, P < 0.02] and 30-s work
capacity (13 +/- 3.7%, P < 0.03) increased significantly in the
Immunocal group, with no change (2 +/- 9.0 and 1 +/- 9.3%) in the
placebo group. Lymphocyte GSH also increased significantly in the
Immunocal group (35.5 +/- 11.04%, P < 0.02), with no change in the
placebo group (-0.9 +/- 9.6%). This is the first study to demonstrate that prolonged supplementation with a product designed to augment
antioxidant defenses resulted in improved volitional performance.
Je ne parle pas aussi bien anglais que Florence le japonais. Je ne suis pas sûr d'avoir tout compris. Il est question d'un produit qui semble diminuer la fatigue musculaire et donc augmenter la performance des muscles à l'entraînement, un peu comme les stéroïdes que s'injectent les athlètes. L'expérience, en double aveugle, donne des résultats significatifs, mais l'échantillon est petit (20 sujets). Par ailleurs, il faut voir si l'étude est réplicable. Ce n'est pas encore fait.
Je ne comprend pas pourquoi votre Gille Proulx s'énerve avec ca? Ce genre de recherches est fréquente. Où serait le miracle dans cette affaire?
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