Intrigué, je suis allé jeter un coup d'oeil sur Pubmed (avec "shark cartilage cancer"). Quelques articles soulignent l'absence de preuves concluantes dans cette affaire (ou la présence de preuves non-concluantes), mais j'ai quand même été surpris de voir quelques résultats de recherches qui suggèrent une certaine efficacité du dit produit (enfin à mon avis).
Voici quelques exemples (désolé, c'est dans la langue de Sheik Spear..):
«It was concluded that shark cartilage, when given alone, significantly increased the survival time of tumour-bearing rats, presumably owing to an anti-angiogenic effect.»
Br J Radiol 2000 Apr;73(868):429-34 Related Articles, Books, LinkOut
Boron neutron capture therapy of the rat 9L gliosarcoma: evaluation of the effects of shark cartilage.
Morris GM, Coderre JA, Micca PL, Lombardo DT, Hopewell JW
Research Institute (University of Oxford), Churchill Hospital, UK.
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».. U-995, has been purified from the cartilage of the blue shark (Prionace glauca). (…)results suggest that the anti-angiogenic effects of U-995 may be be due to interference with the proliferation and migration of HUVECs as well as inhibition of collagenolysis, thereby leading to inhibition of both angiogenesis and tumor cell growth»
Anticancer Res 1998 Nov-Dec;18(6A):4435-41 Related Articles, Books, LinkOut
Effect of U-995, a potent shark cartilage-derived angiogenesis inhibitor, on anti-angiogenesis and anti-tumor activities.
Sheu JR, Fu CC, Tsai ML, Chung WJ
Cancer Research Center, Gwo-Chyang GMP Pharmaceutical Co., Ltd., Tainan, Taiwan. acesane@ms4.hinet.net
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«Guanidine extraction and crude fractionation of Japanese shark cartilage by ultrafiltration on a molecular weight basis were conducted and the antiangiogenic activities were assayed as to the inhibitions of tumor and embryonic angiogenesis. Significant inhibition of angiogenesis was found, and there was a linear relationship between the results of the two assays.»
Cancer Lett 1990 Jun 15;51(3):181-6 Related Articles, Books
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«A novel angiogenic inhibitor derived from Japanese shark cartilage (I). Extraction and estimation of inhibitory activities toward tumor and embryonic angiogenesis.»
Oikawa T, Ashino-Fuse H, Shimamura M, Koide U, Iwaguchi T
Department of Cancer Therapeutics, Tokyo Metropolitan Institute of Medical Science, Japan.
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J'avoue que ça me laisse un peu perplexe, aussi j'aimerais avoir l'opinion de gens qui sont dans des domaines connexes et sans doute mieux informés. Et, coup de chance.., yen a justement sur ce forum ! Enfin bref, qu'en pensez-vous ? Si c'est pas trop indiscret.
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